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About PDR-Chiral |
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Our Company PDR-Chiral Inc is a manufacturer of diode laser-based polarimeters used for the measurement of optically active compounds. The new Advanced Laser Polarimeter can be used for laboratory or on-line measurement of a sample's optical activity. PDR-Chiral currently distributes its products through a series of manuafacturer's representatives here in the US. We will soon be adding agents in Europe and Asia. In addition, PDR-Chiral Inc is a HP Channel Partner. You can visit HP at their web site by clicking here.
Our Product The Advanced Laser Polarimeter (A.L.P.) can be used to provide an analytical chemist with information about an optically active compound's enantiomeric ratio, in real-time. In some cases, it can even provide this information without complete resolution of the enantiomers. The low noise, opto-electronic design results in a detection limit of 25-microdegrees, making the instrument the chiral detection leader in sensitivity, stability and convenience. The A.L.P. is commonly used in conjunction with high performance liquid chromotography (HPLC), HPLC-mass spectrometry (LC-MS), flow injection analysis (FIA) and supercritical fluid chromatography (SFC). It can also be used as an inline monitor for preparative-scale chromatography, simulated moving bed chromatography (SMB) and process-scale production control. General Overview Optical activity is usually indicative of biological activity, past or present. The ability to accurately and precisely measure optical activity is a key technology in the pharmaceutical, food technology and biotechnology industries, the clinical laboratory, and in the development and optimization of new therapeutic drugs. Many antibiotic substances, including penicillins, erythromycins, gentamicins, and neomycins, are produced by living organisms. Subtle changes in the growth conditions of the producing organism can result in a variety of similar analogs which differ only slightly in their composition. Other important applications involve this general theme that the physiological systems of living organisms are designed to recognize only one enantiomer of an enantiomeric pair. However, it has been shown that one member of these related analogs usually has maximum antibacterial activity with minimal human toxicity, while another may have the opposite effect. Thus, the analysis of these materials is an ongoing concern with important ramifications in terms of human health. Since these materials are produced by living organisms, they are usually chiral and possess the property of optical activity. Thus, polarimetric detection is ideally suited to such studies. Please check back with us from time to time as we are updating and adding new and important industry information on a regular basis. Our goal is to provide the internet community with a definitive resource for Chiral-related information. Thank you for visiting our web site, |
